Used 2021 Mercedes-Benz E-Class for Sale Nationwide
92 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 81 currently listed for sale and an average price of $76,502.00 CAD, 29.6% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favourably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
100.0% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features a luxurious interior, updated infotainment systems, and several powertrain options, including a hybrid inline-six engine that balances performance and efficiency.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall
Summary
With 81 currently listed for sale and an average price of $76,502.00 CAD, 29.6% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favourably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
100.0% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features a luxurious interior, updated infotainment systems, and several powertrain options, including a hybrid inline-six engine that balances performance and efficiency.
Why it stands out
The 2021 Mercedes-Benz E-Class captivates car buyers with its impeccable blend of luxury, performance, and technological advancements. With its midsize sedan structure, the E-Class presents a versatile choice, featuring multiple body styles and a range of engines—including an innovative hybrid inline-six powertrain that enhances both power and efficiency. This model year also showcases a refreshed aesthetic, boasting modest exterior styling changes that align closely with the modern Mercedes design ethos, aptly termed "sensual purity." Inside, the E-Class impresses with a lavish cockpit complete with high-quality materials, spacious seating, and an advanced MBUX infotainment system that elevates user interaction. While some owners express concerns over pricing and the availability of certain features, the overall experience remains one of comfort and sophistication, making it a standout option in the luxury vehicle market.
Other model years to consider
- Average price: $50,119.00 CAD
- Good/great deal percentage: 27.2%
- User rating: 5 / 5
- Total listings: 114
- Average price: $35,325.00 CAD
- Good/great deal percentage: 33.1%
- User rating: 4.76 / 5
- Total listings: 130
- Average price: $72,275.00 CAD
- Good/great deal percentage: 40.6%
- User rating: 5 / 5
- Total listings: 64
This analysis is based on CarGurus' proprietary market data from June 22, 2026, CarGurus experts' opinions, and generative AI.
4.7 Overall rating
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ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
Elvis K. N
Reviewed a 2021 Mercedes-Benz E-Class on Jan 29, 2023
Very nice car but does not have active lane keeping assist.
Elvis E
Reviewed a 2021 Mercedes-Benz E 350 RWD on Apr 30, 2023
Best Car Ever! Great gas mileage. No problems so far at all! This is my 2nd Mercedes E-Class and I have no regrets buying it. Has great power. Can go really fast in seconds. If you like sporty exterior and luxury interior then this Mercedes Benz E350 2021 is the car for you!
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 350 4MATIC | $56,750 |
| AMG E 53 Coupe 4MATIC | $76,250 |
| E 450 4MATIC Cabriolet AWD | $74,450 |
| E 450 4MATIC Coupe AWD | $67,450 |
| AMG E 63 S Wagon 4MATIC | $112,450 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
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