Used 2021 Mercedes-Benz E-Class for Sale Nationwide
79 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 77 currently listed for sale and an average price of $67,363.00 CAD, 28.6% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favourably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars and CarGurus experts gave it an 8.33 / 10.
100.0% of 2021 E-Class models on CarGurus are accident free.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall
Summary
With 77 currently listed for sale and an average price of $67,363.00 CAD, 28.6% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favourably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars and CarGurus experts gave it an 8.33 / 10.
100.0% of 2021 E-Class models on CarGurus are accident free.
Why it stands out
The 2021 Mercedes-Benz E-Class stands out as a highly versatile midsize luxury car, with the brand describing it as its most practical and versatile model. It is offered in four body styles, with four engines and dozens of colour schemes, so buyers can tailor it toward comfort, performance, or a more restrained approach depending on how they configure it. That breadth is part of its appeal: the E-Class can be quiet and understated or more expressive and powerful, while still aiming to feel like a polished everyday luxury car.
For 2021, the E-Class receives a mid-cycle update for the infotainment system, engines, and exterior styling, which helps keep it current without changing its core character. The tested Mercedes-AMG E53 uses a mild-hybrid inline-6 powertrain, underscoring that this car can also lean into performance. At the same time, the ownership feedback suggests the E-Class is admired for its luxury, performance, beautiful design, and comfortable interior, though some shoppers may find it overpriced and may miss certain features such as active lane keeping assist.
Other model years to consider
- Average price: $45,939.00 CAD
- Good/great deal percentage: 27.8%
- User rating: 5 / 5
- Total listings: 108
- Average price: $25,695.00 CAD
- Good/great deal percentage: 37.5%
- User rating: 4.78 / 5
- Total listings: 112
- Average price: $35,821.00 CAD
- Good/great deal percentage: 34.6%
- User rating: 4.76 / 5
- Total listings: 127
This analysis is based on CarGurus' proprietary market data from August 10, 2026, CarGurus experts' opinions, and generative AI.
4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
Elvis K. N
Reviewed a 2021 Mercedes-Benz E-Class on Jan 29, 2023
Very nice car but does not have active lane keeping assist.
Elvis E
Reviewed a 2021 Mercedes-Benz E 350 RWD on Apr 30, 2023
Best Car Ever! Great gas mileage. No problems so far at all! This is my 2nd Mercedes E-Class and I have no regrets buying it. Has great power. Can go really fast in seconds. If you like sporty exterior and luxury interior then this Mercedes Benz E350 2021 is the car for you!
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 450 4MATIC Coupe AWD | $67,450 |
| E 350 4MATIC | $56,750 |
| E 450 4MATIC Cabriolet AWD | $74,450 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| AMG E 63 S Wagon 4MATIC | $112,450 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| AMG E 53 Cabriolet 4MATIC | $82,850 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
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