2021 Mercedes-Benz E-Class Reviews, Pricing & Specs















Expert review
For 2021 there are modest and becoming changes for the supreme midsize Mercedes-Benz E-Class sedan.
When money is but a mild concern, a brand-new Mercedes-Benz is a reasonable purchase. The Mercedes-Benz E-Class is the company's most practical and versatile car, as high-quality and necessary in a nice garage as a Kitchen-Aid mixer is in a baker's kitchen. It offers four body styles, four engines, and dozens of colour schemes. Fast or efficient? Loud or library quiet? Modest or rich as hell? The E-Class, the brand's midsize car, is all of those things, depending on which of the 13 models you order and how deep into the options list you dive. For 2021, the E-Class receives a mid-cycle update for the infotainment system, engines, and exterior styling. We tested the Mercedes-AMG E53 that features a mild-hybrid inline-6 powertrain.
out of 10 expert review

What owners say
"Overall, owners love the 2021 Mercedes-Benz E-Class for its blend of luxury, performance, and beautiful design. Many appreciate its powerful engine and comfortable interior, while also enjoying the advanced features. However, some drivers feel it's overpriced and mention the absence of certain features like active lane keeping assist. The mixed opinions on the use of artificial leather also indicate that some expect a more premium feel from a luxury brand."
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
March 2, 2026I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
January 9, 2026Very nice car but does not have active lane keeping assist.
January 29, 2023What owners say
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
March 2, 2026I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
January 9, 2026Very nice car but does not have active lane keeping assist.
January 29, 2023Best Car Ever! Great gas mileage. No problems so far at all! This is my 2nd Mercedes E-Class and I have no regrets buying it. Has great power. Can go really fast in seconds. If you like sporty exterior and luxury interior then this Mercedes Benz E350 2021 is the car for you!
April 30, 2023I’m not sure this is a great value but it does come with beautiful styling in my opinion and the interior is a work of art. Yes a Lexus will likely come with fewer maintenance issues and last longer but other than the LC you’ll be stuck with a boring uglier car that much longer.
February 14, 2023You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.
June 2, 2024Does everything but make coffee! Fantastic automobile. Fast, manuevers well, and comfortable! Looks great, too.
October 14, 2021Over priced for the mileage. Desire real Leather seats, not the artificial leather
February 12, 2024The e63s Is The Quintessential Auto... Best Of Both Worlds Coming Together, Sport And Luxury... The Mercedes V8 Is Going Into Extinction... So If You Ever Want One, Get It Now...
September 1, 2022Ive owned many Mercedes over the years but always come back to Model E. Best size, forward technology and usually handsome exterior/interior
May 2, 2024Trims & specs
Base MSRP N/A | Seating 5 |
Engine N/A | Cargo Capacity N/A |
Combined MPG N/A | Drivetrain N/A |
Base MSRP $67,450 | Seating 4 |
Engine 3.0L 362 hp I6 | Cargo Capacity 10.0 cu ft |
Combined MPG 26 | Drivetrain AWD |
Base MSRP N/A | Seating N/A |
Engine N/A | Cargo Capacity N/A |
Combined MPG N/A | Drivetrain N/A |
Base MSRP $107,500 | Seating 5 |
Engine 4.0L 603 hp V8 | Cargo Capacity 13.1 cu ft |
Combined MPG 19 | Drivetrain AWD |
Base MSRP $62,000 | Seating 5 |
Engine 3.0L 362 hp I6 | Cargo Capacity 13.1 cu ft |
Combined MPG 26 | Drivetrain AWD |
Base MSRP N/A | Seating 5 |
Engine N/A | Cargo Capacity N/A |
Combined MPG N/A | Drivetrain N/A |
Base MSRP $64,950 | Seating 4 |
Engine 3.0L 362 hp I6 | Cargo Capacity 10.0 cu ft |
Combined MPG 27 | Drivetrain RWD |
Base MSRP $112,450 | Seating 5 |
Engine 4.0L 603 hp V8 | Cargo Capacity 35.0 cu ft |
Combined MPG 19 | Drivetrain AWD |
Base MSRP $71,950 | Seating 4 |
Engine 3.0L 362 hp I6 | Cargo Capacity 9.5 cu ft |
Combined MPG 26 | Drivetrain RWD |
Base MSRP $82,850 | Seating 4 |
Engine 3.0L 429 hp I6 | Cargo Capacity 9.5 cu ft |
Combined MPG 24 | Drivetrain AWD |
Base MSRP $73,900 | Seating 5 |
Engine 3.0L 429 hp I6 | Cargo Capacity 13.1 cu ft |
Combined MPG 25 | Drivetrain AWD |
Base MSRP $74,450 | Seating 4 |
Engine 3.0L 362 hp I6 | Cargo Capacity 9.5 cu ft |
Combined MPG 26 | Drivetrain AWD |
Base MSRP N/A | Seating N/A |
Engine N/A | Cargo Capacity N/A |
Combined MPG N/A | Drivetrain N/A |
Base MSRP $76,250 | Seating 4 |
Engine 3.0L 429 hp I6 | Cargo Capacity 10.0 cu ft |
Combined MPG 24 | Drivetrain AWD |
Base MSRP $56,750 | Seating 5 |
Engine 2.0L 255 hp I4 | Cargo Capacity 13.1 cu ft |
Combined MPG 26 | Drivetrain AWD |
Base MSRP $54,250 | Seating 5 |
Engine 2.0L 255 hp I4 | Cargo Capacity 13.1 cu ft |
Combined MPG 26 | Drivetrain RWD |
Pricing trends
MSRP range
$54,250 - $112,450
Current avg. market price
$59,412
Trending down by 5.6% this month
May 2026 - October 2026













