Used 2021 Mercedes-Benz E-Class for Sale near Alberta

How much does the 2021 Mercedes-Benz E-Class cost?

Prices have softened 20.09% compared to this time last year, making it a favourable time to shop this model year.

There are 81 listings available, which gives you a modest amount of inventory to compare.

Is the 2021 Mercedes-Benz E-Class a good car?

Yes — the 2021 Mercedes-Benz E-Class earns a 4.7/5 user rating and an 8.33/10 expert rating. The model scores 10/10 across Technology and Safety.

Owners consistently praise its luxury, performance, and beautiful design, along with the comfortable interior and advanced features. It also stands out as a highly versatile midsize luxury car, with enough breadth to suit buyers who want something fast or efficient, loud or library quiet, or modest or richly equipped.

With 38.3% of listings marked as good or great deals, you have a decent chance of finding a competitively priced example.

Is the 2021 Mercedes-Benz E-Class reliable?

Owners rate it 4.7/5, a strong signal of long-term satisfaction.

The owner feedback points to a car that feels dependable in daily use, with many buyers praising its comfortable interior and advanced features. The expert assessment also describes it as a quiet and excellent choice for a car this size, which supports the sense that it is built to be easy to live with over the long term.

The main ownership risk for used buyers is cost: this is a complex, expensive luxury car, so repairs and upkeep can be more demanding than on a mainstream model.

What should I look for when buying a used 2021 Mercedes-Benz E-Class?

Key things to evaluate:

• Trim level: The cabin is richly finished even in baser trims, but the Luxury package’s smaller wheels and softer-riding, slightly taller suspension are no longer part of the classic hood-ornament look. If you want the most traditional Mercedes feel, pay close attention to how the car is equipped.
• Powertrain: The E350 uses a 2.0-litre turbo four-cylinder that is fine for everyday driving but underwhelming for a luxury car at this price. The E450’s electrified 3.0-litre inline-six is quiet and excellent, while the AMG E53 adds stronger performance with 429 hp and 384 lb-ft.
• Safety package: Forward automatic emergency braking, a driver-attention monitor, and blind-spot monitoring are standard. Other driver-assist features are optional, so check carefully for the equipment you want.
• Infotainment: The 2021 update brings MBUX with touch, swipe, and voice control, plus two 12-inch screens and a standard digital instrument display. Apple CarPlay and Android Auto are standard, but they are not wireless, and the system does not update over the air.
• Fuel efficiency: The E53 sedan is rated at 9.5 L/100 km combined, while the E63 sedan is rated at 12.8 L/100 km combined. The E450 4Matic sedan returns 9.2 L/100 km combined, and the E350 4Matic sedan returns 9.4 L/100 km combined.

Which 2021 Mercedes-Benz E-Class trim should I buy?

The 2021 Mercedes-Benz E-Class is offered in 13 trim levels: E350, E450 4Matic, Mercedes-AMG E53, Mercedes-AMG E63 S, sedan, wagon, coupe, and convertible.

Here's the short version:

• E350: This is the entry point, and it makes sense if you want the E-Class experience with the least complexity. It still gives you the upscale cabin and the updated tech, but the four-cylinder engine is the least convincing part of the lineup.
• E450 4Matic: This is the best-value choice for most shoppers. The electrified inline-six is quiet, strong, and better suited to the car’s luxury mission, while the standard AWD adds all-weather confidence.
• Mercedes-AMG E53: Choose this if you want a sharper, faster E-Class without jumping all the way to the top-performance model. It adds serious pace, rear-biased AWD, and variable-rate air suspension, but it is less efficient and more expensive to run.
• Mercedes-AMG E63 S: This is the full-performance choice, with a hand-built V8, 603 hp, and a much more aggressive chassis. It is the one to buy only if outright performance matters more than comfort, cost, or restraint.

Forward automatic emergency braking, a driver-attention monitor, and blind-spot monitoring are standard, while other driver-assist features remain optional.

Is now a good time to buy a used 2021 Mercedes-Benz E-Class?

This is a moderate market for selective buyers, so it rewards patience and comparison shopping.

• Deal availability: 38.3% of listings are priced as good or great deals.
• Inventory: There are 81 listings available.
• Price trend: Prices have softened 20.09% compared with last year.

If you find a listing below $62,239 CAD, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2021 Mercedes-Benz E-Class's resale value?

The current average of $62,239 CAD sits slightly below last year's $77,891 CAD.

That price movement suggests the market has already adjusted downward, which can make the car more attractive to used buyers today. For a future seller, it also means there may be less room for appreciation unless the vehicle is especially well equipped or exceptionally clean.

Because the E-Class is a desirable luxury model with strong owner satisfaction, demand should remain healthy for the right example. Well-kept cars with the most appealing equipment and powertrains should hold their value better than bare-bones or heavily used ones.

Vehicles with strong owner satisfaction ratings, like this model year's 4.7/5, tend to retain buyer demand, which supports resale value over time.

Is the 2021 Mercedes-Benz E-Class safe?

The 2021 E-Class sedan and wagon earn a five-star overall rating from NHTSA, with five-star ratings in frontal and side crash tests and for rollover vulnerability, though the driver's side received a four-star rating in the frontal crash test.

It earns a 10/10 safety score from our experts.

Forward automatic emergency braking, a driver-attention monitor, and blind-spot monitoring are standard. Other driver-assist features are optional, and some safety features are not available from any other automaker. The 2020 E-Class sedan was rated a Top Safety Pick+ by IIHS, but the 2021 text does not repeat that result for this model year.

Should I buy a 2021 Mercedes-Benz E-Class or consider a different year?

If you're weighing the 2021 against nearby model years, here's how to think about it:

Choose the 2021 if:

• 38.3% of listings are priced as good or great deals.
• Price trend: Prices have softened 20.09% compared with last year.
• Owners rate it 4.7/5 — a strong satisfaction signal.
• The 2021 refresh updates the infotainment system, engines, and exterior styling.

Consider the 2022 if:

• At $54,496 CAD, the 2022 costs less than the current year's $62,239 CAD average.
• It changes very little after the 2021 refresh.

The bottom line: The 2021 is the better pick if you want the refreshed E-Class experience with stronger tech and broader powertrain choice. If your priority is spending less and you do not need the latest update, the 2022 is the simpler value play.

These recommendations are based on CarGurus' proprietary market data from October 13, 2026, CarGurus experts' opinions, and generative AI.