Used 2022 Mercedes-Benz E-Class for SaleNationwide

How much does the 2022 Mercedes-Benz E-Class cost?

Prices have softened 13.12% compared to this time last year, making it a favourable time to shop this model year.

There are 75 listings available, which suggests a healthy amount of inventory for shoppers.

Is the 2022 Mercedes-Benz E-Class a good car?

Yes — it earns a 5/5 user rating and an 8.2/10 expert rating. The standout strength is Safety at 10/10.

The 2022 Mercedes-Benz E-Class leans into refinement and restraint, with a polished, mature luxury-car feel after its substantial 2021 refresh. It stands out for its rare body-style variety, including coupe, convertible, sedan, and station wagon forms, and it continues to project the upscale character Mercedes-Benz buyers expect. For you, that means a strong fit if you want a sophisticated luxury car with everyday usability and a premium cabin experience.

The market also shows 37.3% of listings as good or great deals, which is a useful sign of value opportunities.

Is the 2022 Mercedes-Benz E-Class reliable?

Owners rate it 5/5, a strong signal of long-term satisfaction.

The 2022 Mercedes-Benz E-Class is presented as a polished, mature luxury car rather than a model chasing constant reinvention, which usually helps confidence in day-to-day ownership. Its turbocharged four-cylinder and six-cylinder powertrains, along with the model’s refined overall character, point to a well-developed package. The expert review also highlights the E-Class as a technological tour de force with legitimate seating for four adults.

Mercedes also builds in a lot of ownership-friendly hardware, including standard safety systems and the MBUX interface, which can make the car feel easier to live with over time. For used buyers, the main long-term risk is cost: this is still a premium Mercedes-Benz, so upkeep and options can add up quickly.

What should I look for when buying a used 2022 Mercedes-Benz E-Class?

Key things to evaluate:

• Trim level: The lineup spans coupe, convertible, sedan, and station wagon body styles, with E350, E450, and AMG E53 variants. Base-form E350 sedans are described as more understated, while the AMG E53 Cabriolet adds AMG styling, larger wheels, a convertible top, matte-blue paint, premium leather, and carbon fibre trim.
• Powertrain: E350 sedans use a turbocharged four-cylinder engine, while E450 variants use a turbo 3.0-litre inline-six with EQ Boost 48-volt mild-hybrid technology. AMG E53 models use a more powerful version of the E450 4Matic engine, paired with AMG Speedshift nine-speed automatic transmission and AMG Performance 4Matic+ variable AWD.
• Safety package: Standard equipment includes forward collision warning with pedestrian detection, automatic emergency braking, blind-spot monitoring, rear cross-traffic alert, Mercedes Pre Safe, and Pre Safe Sound. The Driver Assistance Package adds adaptive cruise control with Active Speed Limit Assist, Active Steering Assist, front automatic braking for cross traffic, Evasive Steering Assist, Active Lane Keeping Assist, Active Blind Spot Assist, Active Emergency Stop Assist, and Pre Safe Plus.
• Infotainment: The E-Class uses MBUX with two 12.3-inch screens, Apple CarPlay, Android Auto, Wi-Fi service, augmented reality navigation overlay, and an available head-up display.
• Fuel efficiency: No fuel-consumption figure is stated in the available data.

Which 2022 Mercedes-Benz E-Class trim should I buy?

The 2022 Mercedes-Benz E-Class is offered in 3 trim levels: E350, E450, AMG E53.

Here's the short version:

• E350: This is the entry point if you want the E-Class experience with the turbocharged four-cylinder engine and the model’s core luxury and safety features. It suits you if you value the badge, comfort, and versatility more than outright performance.
• E450: This is the best-value choice if you want the stronger turbo 3.0-litre inline-six with EQ Boost mild-hybrid technology and a more robust all-round driving experience. It adds the most appealing balance of power and refinement for many shoppers.
• AMG E53: Choose this if you want the most performance-focused version, with AMG tuning, 429 horsepower, AMG suspension, performance exhaust, and the most dramatic cabin and exterior presentation.

The Driver Assistance Package is the safety-package upgrade to look for if you want the fullest set of driver aids.

Is now a good time to buy a used 2022 Mercedes-Benz E-Class?

This looks like a moderate, selective buyer’s market, so you have room to compare listings carefully and wait for the right example.

• Deal availability: 37.3% of listings are priced as good or great deals.
• Inventory: There are 75 listings available.
• Price trend: Prices have softened 13.12% compared with last year.

If you find a listing below $53,551 CAD, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2022 Mercedes-Benz E-Class's resale value?

The current average of $54,822 CAD sits slightly below last year's $63,101 CAD.

That price movement suggests the market has already adjusted downward, which can help you buy more confidently today. For a future seller, it also means resale value may depend more heavily on condition, mileage, and equipment than on broad market momentum. Well-kept examples with desirable trims and strong option content should still attract attention, especially in a model with this much luxury appeal.

Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.

Is the 2022 Mercedes-Benz E-Class safe?

The 2022 Mercedes-Benz E-Class earns a 10/10 safety score from our experts.

It has standard forward collision warning with pedestrian detection, automatic emergency braking, blind-spot monitoring, rear cross-traffic alert, Mercedes Pre Safe, and Pre Safe Sound. The E-Class Cabriolet also includes pop-up rollbars for rollover protection, and Active Parking Assist plus a surround-view camera system are standard on the AMG E53. The Driver Assistance Package adds adaptive cruise control, lane-centring assistance, lane-keeping support, blind-spot assist, evasive steering assist, and rear-collision preparation.

Should I buy a 2022 Mercedes-Benz E-Class or consider a different year?

If you're weighing the 2022 against nearby model years, here's how to think about it:

Choose the 2022 if:

• 37.3% of listings are priced as good or great deals.
• Price trend: Prices have softened 13.12% compared with last year.
• Owners rate it 5/5 — a strong satisfaction signal.
• It keeps the polished, mature feel of the refreshed E-Class while adding modest updates like new paint colours and rear USB charging ports on coupe and convertible body styles.

Consider the 2021 if:

• At $59,630 CAD, the 2021 costs more than the current year's $54,822 CAD average.
• It offers broad versatility with four body styles, four engines, and a refreshed infotainment and styling update.

The bottom line: If you want the better-priced version of this generation, the 2022 is the smarter default choice. If you are shopping strictly on price and want a similarly versatile luxury package, the 2021 can still make sense, but you will likely pay more for it.

How does the 2022 Mercedes-Benz E-Class compare to the 2022 BMW 5 Series?

Read our full side-by-side expert comparison here.

These recommendations are based on CarGurus' proprietary market data from November 4, 2026, CarGurus experts' opinions, and generative AI.