Used 2022 Mercedes-Benz E-Class for SaleNationwide

How much does the 2022 Mercedes-Benz E-Class cost?

Prices have softened 14.17% compared to this time last year, making it a favourable time to shop this model year.

There are 69 listings available, which suggests a modest amount of inventory for you to compare.

Is the 2022 Mercedes-Benz E-Class a good car?

Yes — it earns a 5/5 user rating and an 8.17/10 expert rating. The standout strength is Safety at 10/10.

The 2022 E-Class is positioned as a mid-size luxury car that prioritises comfort, presence, and refinement, and it was already substantially refreshed for 2021, so the 2022 lineup changes very little. That makes it a polished choice if you want a well-sorted luxury car rather than one still working through a major redesign. In Canada, the range also leans into all-weather usability with standard 4Matic AWD on the lineup described in the source.

Good and great deals account for 34.8% of listings, which gives you a reasonable chance of finding a competitive example.

Is the 2022 Mercedes-Benz E-Class reliable?

Owners rate it 5/5, a strong signal of long-term satisfaction.

The 2022 E-Class is presented as a well-sorted, mid-cycle product rather than a fresh redesign, which generally supports confidence in how it has been developed and refined. The expert review also describes the model as a technological tour de force with legitimate seating for four adults, and the powertrain is framed as robust and responsive across the rev range. Mercedes’ EQ Boost mild-hybrid system is described as using a 48-volt electrical system and integrated starter generator to improve both power output and efficiency.

If you buy used, the main long-term ownership risk is cost: this is a luxury model with complex systems, so repairs and options can be expensive if the car was heavily equipped or poorly maintained.

What should I look for when buying a used 2022 Mercedes-Benz E-Class?

Key things to evaluate:

• Trim level: The lineup spans coupe, convertible, sedan, and station wagon body styles, and the source notes that the AMG E53 Cabriolet adds AMG styling, larger wheels, a convertible top, matte-blue paint, premium leather, and carbon fibre trim. Base versions are described as more understated, so you should check whether the car you’re considering has the look and equipment level you want.
• Powertrain: The E350 uses a turbocharged four-cylinder engine, while E450 versions use a turbo 3.0-litre inline-six with EQ Boost mild-hybrid technology. The AMG E53 uses a more powerful version of that inline-six, with 429 horsepower and 384 lb-ft of torque.
• Safety package: Standard equipment includes forward collision warning with pedestrian detection, automatic emergency braking, blind-spot monitoring, rear cross-traffic alert, Mercedes Pre Safe, and Pre Safe Sound. The Driver Assistance Package adds adaptive cruise control with Active Speed Limit Assist, Active Steering Assist, front automatic braking for cross traffic, Evasive Steering Assist, Active Lane Keeping Assist, Active Blind Spot Assist, Active Emergency Stop Assist, and Pre Safe Plus.
• Infotainment: The E-Class uses MBUX with two 12.3-inch screens, Apple CarPlay, Android Auto, Wi-Fi service, and an augmented reality navigation overlay. A head-up display is also available.
• Fuel efficiency: The source says the EQ Boost system is intended to improve both power output and efficiency, but it does not provide a fuel-consumption figure.

Which 2022 Mercedes-Benz E-Class trim should I buy?

The 2022 Mercedes-Benz E-Class is offered in 4 trim levels: E350, E450, AMG E53, and AMG E53 Cabriolet.

Here's the short version:

• E350: This is the entry point if you want the E-Class experience with the turbocharged four-cylinder engine. It suits you if you care more about the luxury ambience and body-style choice than maximum performance.
• E450: This is the best-value trim if you want the broader appeal of the turbo 3.0-litre inline-six with EQ Boost, plus the stronger all-round balance of performance and refinement.
• AMG E53: Choose this if you want the more powerful AMG-tuned version of the inline-six, along with the sharper character, AMG Dynamic Select modes, AMG-tuned air suspension, and AMG performance exhaust.
• AMG E53 Cabriolet: Pick this if you want the open-top experience and the most dramatic style. It adds the convertible body style and the luxury-heavy presentation that the source highlights as especially striking.

The safety package note to keep in mind is that most other safety features are bundled into the extra-cost Driver Assistance Package.

Is now a good time to buy a used 2022 Mercedes-Benz E-Class?

This looks like a moderate, selective buyer’s market, so you can be patient and still find worthwhile listings.

• Deal availability: 34.8% of listings are priced as good or great deals.
• Inventory: There are 69 listings available.
• Price trend: Prices have softened 14.17% compared with last year.

If you find a listing below $54,493 CAD, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2022 Mercedes-Benz E-Class's resale value?

The current average of $54,893 CAD sits slightly below last year's $63,952 CAD.

That price drop suggests the market has already adjusted downward, which can help you as a buyer today but may limit upside if you plan to resell soon. For a future seller, the key takeaway is that a well-kept example with desirable equipment and strong presentation should still stand out, but broad market softness can cap how quickly values recover. The model’s luxury positioning and body-style variety should help maintain interest, especially for shoppers who want comfort and refinement.

Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.

Is the 2022 Mercedes-Benz E-Class safe?

The 2022 Mercedes-Benz E-Class earns a 10/10 safety score from our experts.

The E-Class has standard forward collision warning with pedestrian detection, automatic emergency braking, blind-spot monitoring, and rear cross-traffic alert. Mercedes Pre Safe and Pre Safe Sound are also standard, and the Cabriolet adds pop-up rollbars for rollover protection. The Driver Assistance Package brings adaptive cruise control with Active Speed Limit Assist, Active Steering Assist, front automatic braking for cross traffic, Evasive Steering Assist, Active Lane Keeping Assist, Active Blind Spot Assist, Active Emergency Stop Assist, and Pre Safe Plus.

Should I buy a 2022 Mercedes-Benz E-Class or consider a different year?

If you're weighing the 2022 against nearby model years, here's how to think about it:

Choose the 2022 if:

• 34.8% of listings are priced as good or great deals.
• Price trend: Prices have softened 14.17% compared with last year.
• Owners rate it 5/5 — a strong satisfaction signal.
• The 2022 lineup drops the E63 and E63 S AMG models and shifts to turbocharged four-cylinder and six-cylinder powertrains.

Consider the 2021 if:

• At $68,586 CAD, the 2021 costs more than the current year's $54,893 CAD average.
• It offers four body styles, four engines, and broad configurability.

The 2022 is the better path if you want the lower average price and a more favourable used-market setup. If you’re price-sensitive and want the broadest possible choice, the 2021 can still appeal, but you’ll pay more for it.

These recommendations are based on CarGurus' proprietary market data from September 15, 2026, CarGurus experts' opinions, and generative AI.