Used 2021 RAM 2500 for Sale nearHamilton, ON

Summary

• With 66 currently listed for sale near Hamilton, ON and an average price of $47,823.00 CAD, 21.2% of 2021 RAM 2500s for sale on CarGurus are rated as good or great deals.

• Favourably reviewed: Owners rated the 2021 RAM 2500 4.69 / 5 stars.

• 100.0% of 2021 RAM 2500 models on CarGurus are accident free.

Why it stands out

The 2021 RAM 2500 stands out as a heavy-duty pickup that leans hard into luxury and technology without losing its work-truck roots. In its current generation, it adopted many of the Ram 1500’s changes, ditched the crosshair grille, and gained LED lighting and a more aerodynamic design. It also received a stronger frame, a new suspension system, and a new transmission, helping it tow more than 15,875 kilograms and handle almost 3,600 kilograms of payload. The RamBox adds a 115-volt outlet with up to 400 watts of power, which is a useful touch for buyers who want a truck that can do more than haul and tow.

Inside, the 2021 RAM 2500 feels more upscale than many people expect from a three-quarter-ton truck. It borrowed heavily from the 1500, with upgraded materials and available luxury amenities, plus a revised instrument cluster, a rotary gear selector, and a standard trailer brake controller. Available equipment includes a 360-degree camera, a 12-inch vertical touchscreen infotainment system with wireless Apple CarPlay and Android Auto, and a Harman Kardon 750-watt, 17-speaker audio system. It also has the ability to monitor up to 12 trailer tyres, which reinforces its towing focus.

For buyers, the appeal is the combination of serious capability and everyday comfort. The 2021 model year added available trailer reverse guidance, building on earlier updates such as rain-sensing wipers and the Uconnect 5 infotainment upgrade. It is available in Regular-, Crew- and Mega-Cab configurations, with standard and long beds depending on trim, and in Canada the trim range includes the Tradesman, Big Horn, Rebel, Laramie, Limited, Limited Longhorn, and Power Wagon. The main drawbacks are that the turbodiesel engine is expensive, the column shifter feels flimsy, and entry and exit can be difficult, but for shoppers who want a refined heavy-duty truck with strong towing credentials, the 2021 RAM 2500 is a compelling choice.

Other model years to consider

• 2025 RAM 2500

  • Average price: $72,667.00 CAD
  • Good/great deal percentage: 37.4%
  • User rating: 5 / 5
  • Total listings: 99

• 2020 RAM 2500

  • Average price: $47,231.00 CAD
  • Good/great deal percentage: 28.6%
  • User rating: 4.85 / 5
  • Total listings: 49

• 2022 RAM 2500

  • Average price: $56,867.00 CAD
  • Good/great deal percentage: 27.0%
  • User rating: 4.81 / 5
  • Total listings: 74

This analysis is based on CarGurus' proprietary market data from September 2, 2026, CarGurus experts' opinions, and generative AI.