Used 2016 Mercedes-Benz S-Class for Sale Nationwide

Summary

• With 51 currently listed for sale and an average price of $42,259.00 CAD, 25.5% of 2016 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.

• Favourably reviewed: Owners rated the 2016 Mercedes-Benz S-Class 3.92 / 5 stars.

• 100.0% of 2016 S-Class models on CarGurus are accident free.

Why it stands out

The 2016 Mercedes-Benz S-Class stands out as a full-size luxury sedan that blends advanced technology with a deeply polished sense of craftsmanship. In the W222 generation, Mercedes gave the car a new aluminium hybrid body shell that significantly cut weight and improved rigidity, making an already whisper-quiet car even more serene. It also featured selectable ambient lighting, a surround-view camera system that integrated multi-modal radar and ultrasonic sensors, and a digital interface spread across two giant 12.3-inch screens under a single panel. For buyers who value comfort and innovation, that combination is a major part of the S-Class appeal.

What makes the 2016 model especially distinctive is how much luxury and technology it packed into a car that was still very much focused on refinement. The interior used wood and metal accents, and the cabin could be equipped with rear executive seating packages, active parking assist, massaging seats, Burmester surround-sound audio, and other luxury additions. The model also offered a plug-in hybrid version in 2016, the S 550e, which produced 329 system horsepower and offered 23 kilometres of electric range according to Natural Resources Canada. That breadth of equipment helps explain why the S-Class has long been seen as Mercedes-Benz’s showcase for new ideas.

There are trade-offs, though. The 2016 Mercedes-Benz S-Class is expensive to buy and maintain, and the source notes that many of its best features were optional. It also points to suspension and electrical systems as common areas of concern, even if the W222 has a better reliability record than its immediate predecessors. For shoppers who want a used luxury car that feels genuinely special, the 2016 S-Class remains compelling because it delivers opulence, strong performance, and a remarkable amount of technology in one package.

Other model years to consider

• 2018 Mercedes-Benz S-Class
  • Average price: $66,285.00 CAD
  • Good/great deal percentage: 29.8%
  • User rating: 4.79 / 5
  • Total listings: 57

This analysis is based on CarGurus' proprietary market data from August 24, 2026, CarGurus experts' opinions, and generative AI.