I have a 2007 Ford Edge it giving me a code po351 and po351p I have changed the plugs and the coils and it still gives the same codes and now the air is coming out hot?

Did you clear the old code? A misfire would not have anything to do with an AC problem. The AC issue may be low refrigerant level.

Yes the codes have been cleared and refrigerant is good?

When you turn the AC on does then compressor clutch engage? Look under the hood while someone turns the AC on and off.

Possible wiring problem, bad connection or bad ECU. https://www.yourmechanic.com/article/p0351-obd-ii-trouble-code- ignition-coil-a-primary-secondary-circuit-malfunction-by-spencer- clayton

No the clutch does not engage

Check the fuse.

According to the fuse box it shows 1 #10 fuse and relay? The fuse looks good but how do I know about the relay?

I just had mine repaired for misfire cylinder #1. New plugs and coil . The ac not working until the tune up . I suspect the computer tells the AC not to engage while under a misfire condition .The AC was also checked and no problem was found . Works perfectly now