2022 Mercedes-Benz GLS vs 2022 Toyota Sienna
Overview | |
MSRP$35,285 | MSRP$77,850 |
Listings104 | Listings15 |
Ratings & Reviews | |
User Reviews | User Reviews |
Expert reviews8.7 out of 10 | Expert reviews7.3 out of 10 |
2022 Toyota Sienna Reviews SummaryThe 2022 Toyota Sienna hybrid minivan rolls into the second model year following a redesign that made it all-new for 2021. Last year’s successful makeover with a standard hybrid powertrain returns unchanged. | |
2022 Mercedes-Benz GLS Reviews SummaryThe SUV that’s now known as the GLS was launched for the 2007 model year as the GL-Class, when Mercedes decided it needed a bigger, more luxurious SUV to sit above the M-Class in its lineup. The GL-Class and M-Class were rebadged the Mercedes-Benz GLS-Class and GLE-Class, respectively, in 2014 when Mercedes introduced a new naming scheme across its lineup. The current version of the GLS was introduced for the 2020 model year, and represents the model’s third generation. It’s aimed at other full-size luxury SUVs, including the BMW X7, Cadillac Escalade, Infiniti QX80, Land Rover Range Rover, Lincoln Navigator, and Lexus LX. Four models are available in Canada: the base six-cylinder GLS 450 4Matic, the GLS 580 4Matic, the AMG GLS 63 4Matic+, and the Mercedes-Maybach GLS 600 4Matic. Availability is currently limited, and specifications for the 2022 model year are not available. However, they are expected to be very close to those listed for 2021, which were used as reference for the information provided here. We tested a U.S.-specification 2022 GLS 450 for this review. | |
No video found | No video found |
Popular Features & Specs | |
Engine2.5L 245 hp I4 Hybrid | Engine3.0L 362 hp I6 |
Drive TrainFWD | Drive TrainAWD |
Seating Capacity8 | Seating Capacity7 |
Horsepower | Horsepower362 hp @ 5500 rpm |
EV Battery Capacity1.9 kWh | EV Battery Capacity |
MPG City36 | MPG City18 |
MPG Highway36 | MPG Highway24 |
Engine | |
Engine Name2.5L 245 hp I4 Hybrid | Engine Name3.0L 362 hp I6 |
Torque | Torque369 lb-ft @ 1600 rpm |
Horsepower | Horsepower362 hp @ 5500 rpm |
DrivetrainFWD | DrivetrainAWD |
Fuel Economy | |
EV Battery Capacity1.9 kWh | EV Battery Capacity |
MPG City36 | MPG City18 |
MPG Highway36 | MPG Highway24 |
Interior | |
Seating Capacity8 | Seating Capacity7 |
Key Features | |
Navigation System | Navigation SystemStandard |
Sunroof/Moonroof | Sunroof/MoonroofStandard |
Safety | |
Front Crash Overall4 | Front Crash Overall |
Side Crash Overall5 | Side Crash Overall |
Dimensions & Capacity | |
Cargo Space33.5 cu ft | Cargo Space17.4 cu ft |
Curb Weight4610 lbs | Curb Weight5467 lbs |
Height68.5 in | Height72.4 in |
Length203.7 in | Length205.0 in |
Width78.5 in | Width84.9 in |
Wheelbase120.5 in | Wheelbase123.4 in |
Maximum Payload1560 lbs | Maximum Payload1808 lbs |
Number of doors4 | Number of doors4 |
Maximum Towing Capacity3500 lbs | Maximum Towing Capacity7700 lbs |
Overview | ||
MSRP | $35,285 | $77,850 |
Listings | ||
Ratings & Reviews | ||
User reviews | ||
Expert reviews | 8.7 out of 10Read full review | 7.3 out of 10Read full review |
Pros & cons | ||
Summary | The 2022 Toyota Sienna hybrid minivan rolls into the second model year following a redesign that made it all-new for 2021. Last year’s successful makeover with a standard hybrid powertrain returns unchanged. | The SUV that’s now known as the GLS was launched for the 2007 model year as the GL-Class, when Mercedes decided it needed a bigger, more luxurious SUV to sit above the M-Class in its lineup. The GL-Class and M-Class were rebadged the Mercedes-Benz GLS-Class and GLE-Class, respectively, in 2014 when Mercedes introduced a new naming scheme across its lineup. The current version of the GLS was introduced for the 2020 model year, and represents the model’s third generation. It’s aimed at other full-size luxury SUVs, including the BMW X7, Cadillac Escalade, Infiniti QX80, Land Rover Range Rover, Lincoln Navigator, and Lexus LX. Four models are available in Canada: the base six-cylinder GLS 450 4Matic, the GLS 580 4Matic, the AMG GLS 63 4Matic+, and the Mercedes-Maybach GLS 600 4Matic. Availability is currently limited, and specifications for the 2022 model year are not available. However, they are expected to be very close to those listed for 2021, which were used as reference for the information provided here. We tested a U.S.-specification 2022 GLS 450 for this review. |
Video | No video found | No video found |
Popular Features & Specs | ||
Engine | 2.5L 245 hp I4 Hybrid | 3.0L 362 hp I6 |
Drive Train | FWD | AWD |
Seating Capacity | 8 | 7 |
Horsepower | 362 hp @ 5500 rpm | |
EV Battery Capacity | 1.9 kWh | |
MPG City | 36 | 18 |
MPG Highway | 36 | 24 |
Engine | ||
Engine Name | 2.5L 245 hp I4 Hybrid | 3.0L 362 hp I6 |
Torque | 369 lb-ft @ 1600 rpm | |
Horsepower | 362 hp @ 5500 rpm | |
Drivetrain | FWD | AWD |
Fuel Economy | ||
EV Battery Capacity | 1.9 kWh | |
MPG City | 36 | 18 |
MPG Highway | 36 | 24 |
Interior | ||
Seating Capacity | 8 | 7 |
Key Features | ||
Navigation System | Standard | |
Sunroof/Moonroof | Standard | |
Safety | ||
Front Crash Overall | 4 | |
Side Crash Overall | 5 | |
Dimensions & Capacity | ||
Cargo Space | 33.5 cu ft | 17.4 cu ft |
Curb Weight | 4610 lbs | 5467 lbs |
Height | 68.5 in | 72.4 in |
Length | 203.7 in | 205.0 in |
Width | 78.5 in | 84.9 in |
Wheelbase | 120.5 in | 123.4 in |
Maximum Payload | 1560 lbs | 1808 lbs |
Number of doors | 4 | 4 |
Maximum Towing Capacity | 3500 lbs | 7700 lbs |
The 2022 Toyota Sienna stood out in a market where minivans were becoming increasingly rare, as many manufacturers shifted focus to SUVs. Despite this trend, Toyota remained committed to the minivan segment, evolving the Sienna over the years. The fourth-generation Sienna, launched in 2021, embraced a more SUV-like aesthetic while retaining its minivan functionality. Its design featured a bold front end and cleverly concealed sliding door channels, giving it a more assertive stance. Inside, the Sienna offered a spacious and practical cabin with ample storage solutions, comfortable seating, and a third-row bench that folded into the floor, making it a versatile choice for families.
In contrast, the 2022 Mercedes-Benz GLS exuded a more understated luxury compared to its flashier competitors. The base GLS 450 model offered a subtle elegance, while the AMG and Maybach versions added visual flair with distinctive design elements. The interior of the GLS was luxurious, featuring high-quality materials and advanced technology. The digital instrument cluster and infotainment touchscreen were seamlessly integrated, providing a modern and sophisticated feel. Despite its luxury status, the GLS's suspension left something to be desired, as it struggled with body control over bumps and corners, detracting from the overall comfort.














The 2022 Toyota Sienna was powered exclusively by a hybrid powertrain, combining a 2.5-litre four-cylinder engine with two electric motors to produce 243 horsepower. This setup offered both front-wheel drive and all-wheel drive options, with the latter adding an additional electric motor for the rear wheels. The Sienna's electronically controlled continuously variable transmission (CVT) contributed to its smooth power delivery and impressive fuel efficiency, with Natural Resources Canada rating it at 6.6 litres per 100 kilometres for FWD models and slightly higher for AWD versions. The Sienna's handling was commendable for a minivan, thanks to its well-engineered suspension system.
The 2022 Mercedes-Benz GLS 450 featured a 3.0-litre turbocharged inline six-cylinder engine paired with a nine-speed automatic transmission and the EQ Boost mild-hybrid system. This combination delivered 362 horsepower and 369 pound-feet of torque, with an additional 21 hp and 184 lb-ft available from the electric motor. The GLS 450's performance was robust, and the inline-six engine provided a smooth and balanced driving experience. However, the GLS's air suspension struggled with body control, leading to excessive motion over bumps and in corners. The GLS 450 boasted a towing capacity of 3,500 kilograms, though some competitors offered higher capabilities.
The 2022 Toyota Sienna excelled in practicality, offering a spacious interior capable of accommodating a full 4x8 sheet of plywood with the tailgate closed. Its sliding second-row seats provided flexibility for cargo and passenger arrangements, with cargo capacities ranging from 949 litres behind the third row to 2,860 litres with the second row folded. The Sienna's power-operated sliding doors and liftgate added convenience, especially when hands were full. With a towing capacity of 1,585 kilograms, the Sienna was well-suited for family adventures.
The 2022 Mercedes-Benz GLS offered a seven-seat configuration with a 60/40 split-folding second-row bench and two third-row seats. An optional six-seat version replaced the bench with captain's chairs. The GLS provided ample legroom, particularly in the second row, thanks to its long wheelbase. Cargo space was competitive, with 355 litres available with all seats in place and expanding to 2,400 litres with the second and third rows folded. The GLS's air suspension facilitated easy loading and unloading, but some ergonomic issues, such as the touchscreen's reach and centre console design, detracted from its overall functionality.
The 2022 Toyota Sienna came equipped with a 9-inch touchscreen infotainment system featuring Apple CarPlay, Android Auto, and SiriusXM. While it lacked wireless connectivity for these features, it offered a range of telematics services and a 12-speaker JBL audio system on higher trims. The Sienna also provided a rear-seat entertainment system with an 11.6-inch display, enhancing the in-car experience for passengers. A digital rearview mirror and Smart Key System were available on select trims, adding to the Sienna's technological appeal.
The 2022 Mercedes-Benz GLS featured the MBUX infotainment system with a 12.3-inch touchscreen and digital instrument cluster. It offered Apple CarPlay, Android Auto, and navigation, along with a 13-speaker Burmester audio system. The voice recognition system, activated by "Hey Mercedes," was particularly user-friendly, allowing for hands-free operation. However, the touchpad controller proved cumbersome, and the navigation system occasionally suggested inefficient routes. Despite these quirks, the GLS's technology suite was comprehensive and advanced.
The 2022 Toyota Sienna was expected to maintain its Top Safety Pick+ rating from the IIHS and five-star rating from the NHTSA. It came standard with Toyota Safety Sense 2.0, which included adaptive cruise control, lane centring, forward collision warning, and automatic emergency braking. The Sienna also featured 10 airbags, blind spot monitoring, and a rear-seat reminder system, making it a safe choice for families.
The 2022 Mercedes-Benz GLS offered a range of standard safety features, including forward collision warning, automatic emergency braking, and blind-spot monitoring. Additional features like adaptive cruise control and advanced driver-assistance systems were available as options. While crash-test ratings were not available at the time, the GLS's safety suite was comprehensive, though some features required additional investment.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2022 Toyota Sienna is 8.7 out of 10, while the 2022 Mercedes-Benz GLS scores 7.3 out of 10. Based on these ratings, the Toyota Sienna emerges as the more highly recommended choice, offering a compelling blend of practicality, efficiency, and safety for families.
Choose the 2022 Mercedes-Benz GLS if:
- You desire a luxury SUV with advanced technology and infotainment.
- You appreciate a smooth and powerful inline-six engine.
- You seek a vehicle with a prestigious brand and upscale design.
Choose the 2022 Toyota Sienna if:
- You prioritize fuel efficiency and a hybrid powertrain.
- You need a versatile and spacious interior for family and cargo.
- You value a comprehensive suite of standard safety features.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2022 Toyota Sienna is 8.7 out of 10, while the 2022 Mercedes-Benz GLS scores 7.3 out of 10. Based on these ratings, the Toyota Sienna emerges as the more highly recommended choice, offering a compelling blend of practicality, efficiency, and safety for families.
Choose the 2022 Mercedes-Benz GLS if:
Shop Now- You desire a luxury SUV with advanced technology and infotainment.
- You appreciate a smooth and powerful inline-six engine.
- You seek a vehicle with a prestigious brand and upscale design.
Choose the 2022 Toyota Sienna if:
Shop Now- You prioritize fuel efficiency and a hybrid powertrain.
- You need a versatile and spacious interior for family and cargo.
- You value a comprehensive suite of standard safety features.

By: CarGurus + AI
At CarGurus, our team of experienced automotive writers remain at the heart of our content operation, conducting hands-on car tests and writing insightful guides that are backed by years of industry experience. To complement this, we are harnessing AI to make our content offering more diverse and more helpful to shoppers than ever. To achieve this, our AI systems are based exclusively on CarGurus content, ratings and data, so that what we produce is both unique to CarGurus, and uniquely helpful to car shoppers.




































