2021 Mercedes-Benz S-Class Reviews, Pricing & Specs

2021 Mercedes-Benz S-Class rear three quarter thumbnail
2021 Mercedes-Benz S-Class profile thumbnail
2021 Mercedes-Benz S-Class dashboard thumbnail
2021 Mercedes-Benz S-Class rear seats thumbnail
2021 Mercedes-Benz S-Class touchscreen thumbnail
2021 Mercedes-Benz S-Class engine thumbnail
2021 Mercedes-Benz S-Class front three quarter thumbnail
2021 Mercedes-Benz S-Class front three quarter thumbnail
2021 Mercedes-Benz S-Class front three quarter thumbnail

$109,800 to $185,400

What owners say

AI Summary · 4 reviews

"Overall, owners are extremely impressed with the 2021 Mercedes-Benz S-Class. They love its luxurious feel, advanced technology, and remarkable performance. Many find the handling and acceleration to be thrilling and enjoyable. However, a few noted issues with the run-flat tires, suggesting that not everything is perfect."

4.0
4 reviews
5
4
3
2
1

The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.

August 28, 2025

This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.

June 5, 2024

This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.

March 23, 2023

Trims & specs

AMG S 63 Cabriolet 4MATIC specifications

Base MSRP

$185,400

Seating

4

Engine

4.0L 603 hp V8

Cargo Capacity

6.9 cu ft

Combined MPG

19

Drivetrain

AWD

Maybach S 580 Sedan 4MATIC specifications

Base MSRP

$184,900

Seating

5

Engine

4.0L 496 hp V8

Cargo Capacity

12.5 cu ft

Combined MPG

20

Drivetrain

AWD

S 560 Cabriolet RWD specifications

Base MSRP

$140,000

Seating

4

Engine

4.0L 463 hp V8

Cargo Capacity

6.9 cu ft

Combined MPG

21

Drivetrain

RWD

AMG S 63 Coupe 4MATIC specifications

Base MSRP

$173,100

Seating

4

Engine

4.0L 603 hp V8

Cargo Capacity

10.4 cu ft

Combined MPG

21

Drivetrain

AWD

S 500 Sedan 4MATIC specifications

Base MSRP

$109,800

Seating

5

Engine

3.0L 429 hp I6

Cargo Capacity

12.9 cu ft

Combined MPG

24

Drivetrain

AWD

S 560 Coupe 4MATIC specifications

Base MSRP

$131,400

Seating

4

Engine

4.0L 463 hp V8

Cargo Capacity

10.4 cu ft

Combined MPG

21

Drivetrain

AWD

S 580 Sedan 4MATIC specifications

Base MSRP

$116,300

Seating

5

Engine

4.0L 496 hp V8

Cargo Capacity

12.9 cu ft

Combined MPG

21

Drivetrain

AWD

Pricing trends

MSRP range

$109,800 - $185,400

Current avg. market price

$86,880

Trending down by 2.9% this month

May 2026 - October 2026

See full price trends

$109,800 to $185,400